Basic Molecular Information

Basic Information

DICL ID
DICL_CP_0324799
PubChem CID
Molecular Formula
C14H13ClN4O
Molecular Weight
288.738 g/mol
Synonyms/Alias
[CHEMBL443165; BDBM50275796; 5-chloro-N-(2-methoxybenzyl)pyrazolo[1;5-a]pyrimidin-7-amine]
InChI Key
QHRAEVKEZZEIFJ-UHFFFAOYSA-N
InChI
InChI=1S/C14H13ClN4O/c1-20-11-5-3-2-4-10(11)9-16-14-8-12(15)18-13-6-7-17-19(13)14/h2-8,16H,9H2,1H3
IUPAC Name
5-chloro-N-[(2-methoxyphenyl)methyl]pyrazolo[1,5-a]pyrimidin-7-amine
CAS Number
N/A (Not available)

Structure Information

Chemical Structure Visualization

SMILES Notation
2D Molecular Drawing
Carbon (C)
Hydrogen (H)
Oxygen (O)
Nitrogen (N)
Sulfur (S)
SDF

33 35 0 0 0 0 0 0 0 0999 V2000
-2.8791 -1.5479 -2.0001 C 0 0 0 0 0 0 0 0 0 0 0 0
-2.0999 -1.1692 -0.8704 O 0 0 0 0 0 0 0 0 0 0 0 0
-2.5404 -0.310...

Experimental Data

Activity Data

Target Ion Channel
Intermediate/Small conductance calcium activated potassium channel subfamily N member 2 (KCa2.2)
Uniprot Accession Number
Function
Blocker
Species
Rattus norvegicus (Rat)
IC50
IC50: 1100 nM
EC50
N/A (Not available)
Ki
N/A (Not available)
Kd
N/A (Not available)
Inhibition
N/A (Not available)

Experimental Conditions

pH
Not mention
Holding Potential
Not specified
Temperature
Not mention
Test Method
Efflux Assay ([86] Rubidium Ion)
Test Species
Not specified

Binding Information

Binding Site
Not specified
Binding Site Residue
Not specified

Disease Information

Related Disease
Not specified

References

URL
N/A (Not available)
PMID
Patent
N/A (Not available)

Computed Properties

Heavy Atom Count
20
Rotatable Bonds
4
logP
3.0034
Complexity
78.3177
TPSA (Ų)
51.45
H-Bond Donors
1
H-Bond Acceptors
5
Ring Count
3
New Search